The primary goal of this study is to examine whether a brief treatment approach for PTSD is equally efficacious in the treatment of active duty service members relative to a first line treatment approach that requires much greater treatment dose.



Eligible Ages
Over 18 Years
Eligible Genders
Accepts Healthy Volunteers

Inclusion Criteria

  • Male and female active duty military personnel who have deployed in support of a post-9/11 conflict seeking treatment for PTSD
  • Diagnosis of PTSD
  • Ability to speak, read and write English
  • Not currently engaged in psychosocial treatment for PTSD
  • Individuals taking psychotropic medications agree to work with their prescriber to remain on stable doses of any prescribed psychotropic medications for the duration of the intervention and through the first follow-up assessment as much as possible and as medically indicated.

Exclusion Criteria

  • Current suicide or homicide risk meriting crisis intervention
  • Active psychosis
  • Moderate to severe brain damage

Study Design

Study Type
Intervention Model
Parallel Assignment
Primary Purpose
Single (Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Written exposure therapy
5 sessions of imaginal exposure therapy.
  • Behavioral: written exposure therapy
    five sessions of writing about traumatic experience.
    Other names:
    • WET
Active Comparator
CPT, cognitive only
12 sessions of cognitive therapy.
  • Behavioral: CPT, cognitive only
    12 sessions of cognitive therapy related to traumatic experience.
    Other names:
    • CPT-C

Recruiting Locations

University of Texas Health Science Center, San Antonio
San Antonio, Texas 78229
Amanda Flores, BA

More Details

Boston VA Research Institute, Inc.

Study Contact

Alan Peterson, Ph.D.
(210) 562-6744

Detailed Description

The goal of this randomized clinical trial is to investigate if a brief, written intervention for posttraumatic stress disorder (PTSD), Written Exposure Therapy (WET), is equally efficacious as an evidenced-based behavioral therapy, Cognitive Processing Therapy-Cognition only (CPT-C), in the treatment of PTSD in active duty military men and women with a diagnosis of PTSD who have deployed in support of a post-9/11. The primary study outcome will be change in symptom severity as assessed by the Clinician Administered PTSD Scale for Diagnostic and Statistical Manual-5 edition (CAPS-5). Independent assessors will evaluate participants using the CAPS-5 at baseline, 10- (post-treatment), 20-, and 30-week intervals after the start of treatment.


Study information shown on this site is derived from ClinicalTrials.gov (a public registry operated by the National Institutes of Health). The listing of studies provided is not certain to be all studies for which you might be eligible. Furthermore, study eligibility requirements can be difficult to understand and may change over time, so it is wise to speak with your medical care provider and individual research study teams when making decisions related to participation.