Brief Treatment for Posttraumatic Stress Disorder

Purpose

The primary goal of this study is to examine whether a brief treatment approach for PTSD is equally efficacious in the treatment of active duty service members relative to a first line treatment approach that requires much greater treatment dose.

Condition

  • PTSD

Eligibility

Eligible Ages
Over 18 Years
Eligible Genders
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Male and female active duty military personnel who have deployed in support of a post-9/11 conflict seeking treatment for PTSD - Diagnosis of PTSD - Ability to speak, read and write English - Not currently engaged in psychosocial treatment for PTSD - Individuals taking psychotropic medications agree to work with their prescriber to remain on stable doses of any prescribed psychotropic medications for the duration of the intervention and through the first follow-up assessment as much as possible and as medically indicated.

Exclusion Criteria

  • Current suicide or homicide risk meriting crisis intervention - Active psychosis - Moderate to severe brain damage

Study Design

Phase
N/A
Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel Assignment
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Written exposure therapy
5 sessions of imaginal exposure therapy.
  • Behavioral: written exposure therapy
    five sessions of writing about traumatic experience.
    Other names:
    • WET
Active Comparator
CPT, cognitive only
12 sessions of cognitive therapy.
  • Behavioral: CPT, cognitive only
    12 sessions of cognitive therapy related to traumatic experience.
    Other names:
    • CPT-C

More Details

Status
Completed
Sponsor
Boston VA Research Institute, Inc.

Study Contact

Detailed Description

The goal of this randomized clinical trial is to investigate if a brief, written intervention for posttraumatic stress disorder (PTSD), Written Exposure Therapy (WET), is non-inferior compared to an evidenced-based behavioral therapy, Cognitive Processing Therapy-Cognition only (CPT-C), in the treatment of PTSD in active duty military men and women with a diagnosis of PTSD who have deployed in support of a post-9/11. The primary study outcome is change in symptom severity as assessed by the Clinician Administered PTSD Scale for Diagnostic and Statistical Manual-5 edition (CAPS-5). Independent assessors evaluated participants using the CAPS-5 at baseline, 10-, 20-, and 30-week after the first treatment session.