Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

Purpose

This research study is collecting and storing samples of tumor tissue, bone marrow, and blood from patients with Ewing sarcoma. Collecting and storing samples of tumor tissue, bone marrow, and blood from patients with cancer to test in the laboratory may help the study of cancer in the future.

Conditions

  • Askin Tumor
  • Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Eligibility

Eligible Ages
Under 21 Years
Eligible Genders
All
Accepts Healthy Volunteers
No

Criteria


Inclusion Criteria:

- Diagnosis of Ewing sarcoma, including peripheral primitive neuroectodermal tumor and
Askin tumor

- Newly diagnosed or recurrent disease

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Arm Groups

ArmDescriptionAssigned Intervention
Observational (biomarker sampling) Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.
  • Other: Laboratory Biomarker Analysis
    Correlative studies

More Details

Status
Completed
Sponsor
Children's Oncology Group

Study Contact

Detailed Description

OBJECTIVES: I. Collect biological specimens, including associated demographic and clinical data, from patients with Ewing sarcoma. II. Provide a repository for long-term storage of Ewing sarcoma-related biological materials. III. Make collected specimens available to qualified researchers to understand the biology of Ewing sarcoma and correlate these results with demographic and clinical data. OUTLINE: This is a multicenter study. Patients undergo collection of tumor specimens, bone marrow, and peripheral blood at diagnosis. Associated demographic and clinical data are collected and archived. Patients who are not enrolled on a therapeutic clinical trial are followed annually.